Open Access

Downloads

Download data is not yet available.

Abstract

Recent studies have demonstrated the potential of in vitro Urena lobata L. hairy roots to inhibit α-glucosidase for supporting the treatment of type 2 diabetes. To increase the productivities of hairy roots with α-glucosidase inhibitory activity in in vitro culture conditions, this study focus on the effects of some metabolic factors such as precursors (L-phenylalanine, L-tyrosine) and elicitors (chitosan, methyl jasmonate, salicylic acid). They were added to the culture media to investigate the growth and α-glucosidase inhibitory activity of Urena lobata L. hairy roots. The results showed that for the effects of precursors, only phenylalanine (1 µM) increased root biomass with the highest of α-glucosidase inhibitory activity on the 25th day of culture. In contrast, tyrosine did not play any role in increasing the biomass and α-glucosidase inhibitory activity in Urena lobata L. hairy roots. For the effects of elicitors, only chitosan (50 mg/L) resulted in hairy roots with α-glucosidase inhibitory activity higher than the control after 3 days in culture medium. Other elicitors such as methyl jasmonate, salicylic acid had lower α-glucosidase inhibitory activity than the control. The results of this study demonstrated the potential of phenylalanine and chitosan in increasing the productivity of in vitro hairy roots with higher α-glucosidase inhibitory activity in Urena lobata L.


 



Author's Affiliation
Article Details

Issue: Vol 4 No 3 (2020): Under Publishing
Page No.: Online First
Published: Sep 11, 2020
Section: Original Research
DOI: https://doi.org/10.32508/stdjns.v4i3.902

 Copyright Info

Creative Commons License

Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Vu, P., Cao, D., & Quach, P. (2020). Effects of some precursors and elicitors on the growth and α-glucosidase inhibitory activity of in vitro Urena lobata L. hairy roots. Science and Technology Development Journal - Natural Sciences, 4(3), Online First. https://doi.org/https://doi.org/10.32508/stdjns.v4i3.902

 Cited by



Article level Metrics by Paperbuzz/Impactstory
Article level Metrics by Altmetrics

 Article Statistics
HTML = 24 times
ONLINE FIRST VERSION   = 4 times
Total   = 4 times

Most read articles by the same author(s)