Open Access


Download data is not yet available.


Current bone regeneration surgeries focus on regenerating damaged bone tissue structures rather than replacing them. Bone-derived hydroxyapatite (HAP) is a natural bone component with good bone resilience, emerging and a promising bone graft material. Factors in the synthesis process are very important to the properties of hydroxyapatite. The purpose of this study is to assess the effect of three different furnaced temperatures on the size and phase purity of the HA crystal. The research consists of the following two stages: after combining physical and chemical methods in the first period to eliminate most of the organic components; bones continue to be heated at temperatures of 600oC, 700oC and 800oC to create the various size of HA crystals in bone particles. Product composition and size of HA crystal are determined by TGA, XRD, FTIR, SEM, EDX methods. The results show that crystal size and phase purity can be controlled and increased with the temperature. In particular, the HA crystal size did not change significantly in the range of 600◦C but increased 10-times above 700◦C. Single crystal HA is expected to form in the range of 600 - 700◦C. After the sample was heated to 600◦C, the organic compounds such as blood and bone marrow were completely burned. In addition, two trace elements, Na and Mg, were not completely removed as in other cases but were still retained inside the bone particle. The Ca/P ratio is 1.63 is similar to the Ca/P ratio found in human bones.

Author's Affiliation
Article Details

Issue: Vol 5 No 1 (2021)
Page No.: 1005-1014
Published: Feb 2, 2021
Section: Original Research

 Copyright Info

Creative Commons License

Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Hà, L., Tien, C., & Tran, D. (2021). The variable size consideration of hydroxyapatite extracted from bovine bone at different temperature furnaces. Science and Technology Development Journal - Natural Sciences, 5(1), 1005-1014.

 Cited by

Article level Metrics by Paperbuzz/Impactstory
Article level Metrics by Altmetrics

 Article Statistics
HTML = 89 times
Download PDF   = 8 times
Total   = 8 times