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MCM-41 mesoporous silica nanoparticles were successfully synthesized by the condensation of tetraorthosilicate precursor (TEOS) using cetyltrimethylammonium bromide (CTAB) as the orientation substance in alkaline (pH = 9–12), deionized water as solvent. The samples were calcinated at 550°C for 5 hours. The structural characteristics of samples were analyzed by using Small angle X-ray diffraction, transmission electron microscopy (TEM), FT-IR and isothermal adsorption of nitrogen. Optimizing the fabrication parameters, MCM-41 particles have been obtained with a spherical shape, size of 80-140 nm, pore diameter of 2–5 nm and surface area (BET) of 986,683 m2g-1. Rhodamine B adsorption of MCM-41 showed that the maximum adsorption capacity value was 299,696 mg/g, suggesting the potential of this material to design of controlled drug delivery systems.

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Issue: Vol 2 No 4 (2018)
Page No.: 95-102
Published: Aug 13, 2019
Section: Original Research

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Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Dau, N., Le, H., & Tran, V. (2019). MCM-41 mesoporous silica anoparticles and their adsorption for targeting drug delivery systems. Science and Technology Development Journal - Natural Sciences, 2(4), 95-102.

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