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Abstract

Gynostemma pentaphyllum Thunb. Makino is a common folk herb used in the treatment of diabetes, hyperlipidemia, cardiovascular, cancer… [1]. This research was conducted to evaluate some bioactivities of the plant such as antioxidant, antimicrobial activity, α-glucosidase and lipase inhibition. Results showed that the ethanol extract of G. pentaphyllum is more active than the folk medicine-aqueous extract. The antimicrobial activity by measuring the zone of inhibition, showed strongest inhibition to Pseudomonas (d = 6,670 mm); the antioxidant activity of ethanol extract tested by DPPH method showed IC50 = 0.317 mg/mL; the ethanol extract also showed outstanding α-glucosidase inhibition activities with IC50 = 0.181 mg/mL and lipase inhibition activity with IC50 = 2.968 mg/mL. The ethanol extract of G. pentaphyll contained active substance groups such as phenols, flavonoids, alkaloids and saponins. This research has proved the potential of G. pentaphyllum ethanol extract as a source of valuable medicine in the treatment of common diseases nowadays.



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Issue: Vol 1 No 6 (2017)
Page No.: 49-57
Published: Dec 7, 2018
Section: Original Research
DOI: https://doi.org/10.32508/stdjns.v1i6.615

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Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Tong, H., Vu, P., Duong, K., & Quach, P. (2018). Biologicalactivities of Gynostemma pentaphyllum (Thunb.) Makino. Science and Technology Development Journal - Natural Sciences, 1(6), 49-57. https://doi.org/https://doi.org/10.32508/stdjns.v1i6.615

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